Saturday, December 29, 2007

Pacific Ocean Death Zone

I saw this video on msnbc.com today:

Dec. 29: NBC's Kerry Sanders reports on a huge mass of garbage floating in the Pacific Ocean that is killing marine life and growing larger each day.


http://www.msnbc.msn.com/id/21134540/#22431379

After watching this video, I feel really disgusted the way people are messing up this beautiful planet. As I get older, I think I am turning into a bleeding-heart liberal.

Okay, it is time to start a new blog on going Green.

Saturday, December 22, 2007

Introducing Community Book: Bookmaking just got a lot more social

I just found out about the Community Book feature on blurb.com.  This is very interesting and may come in handy with the book project being discussed on reginaspektor brümstix.  Well, I need another project like I need a hole in my head, haha.

 Blurberati Blog » Introducing Community Book: Bookmaking just got a lot more social

Wednesday, December 5, 2007

Factsheets : MQ-1 Predator Unmanned Aerial Vehicle

I arranged a presentation by a Predator Sensor Operator to my daughter's high school Robotics Club today after school. It is some amazing stuff!



Factsheets : MQ-1 Predator Unmanned Aerial Vehicle

Sunday, November 25, 2007

I lost my cookies.

This is very strange. I can't seem to find my cookies folder on my Windows XP computer. I have done a folder search and nothing came up. Under the folder options, I have selected "Show hidden files and folders."

I know the folder is under C:\Documents and Settings\username\Cookies, but it is just not showing up.

There appears to be a new option which I must have overlooked in the folder options/view window. I need to unchecked "Hide protected operating system files." Once it is unchecked the folder showed up as a light gray hidden folder.

The other thing I could have done is just type "cookies" as a run command and the folder will show up.

Saturday, November 24, 2007

Review of Smartparts 8" Digital Picture Frame SP8EM

Digital Picture Frames are very popular these days. It is a wonderful way to display all the digital photos that seem to clog up my hard drives. The Smartparts 8" Digital Picture Frame was on sale at Costco this weekend and here is my first impression. The model number I have is the 8" SP8EM. There are many other models available at the Smartparts web site.





The entire wood frame size is about 9-5/8" x 8-1/4" with the LCD screen size of 6-1/4" x 4-3/4". The resolution of the LCD is 800x600. Therefore, the size of the LCD is just a little larger than a regular 4x6 photo. The LCD size is just about right for me.

What's inside the box:

  • LCD Picture frame

  • Remote control

  • AC Power adapter

  • USB cord to connect to a PC

  • Removable stand (Plastic piece)

Getting Started:

Getting started is easy. Plug the power cord into the LCD frame and turn the unit on. The slide show starts automatically using the 5 sample slides saved on the internal 128 MB flash memory. I inserted a 256 MB compact flash (CF) card with about 20 jpg photos at 1800x1200 size and they were automatically displayed in the slide show. The jpg files on the CF card do not need to be transferred to the internal memory to be displayed. The photos displayed just fine from the CF card directly. Therefore, if you have a large memory card, the number of photos that can be displayed can be into the thousands.

There are 2 slots for memory cards- CF card and SD card. There is also another USB port probably for an USB memory stick. If the LCD frame is connected to the USB port of a PC, Windows automatically detects the 2 removable card slots and the internal flash memory. Files can then be copied to the removable memory card or internal memory by using copy and paste within Windows. There is a program called Optipix Pro stored in the internal flash memory. Clicking on the setup program automatically install the Windows program.

The OptiPix program basically resize any jpg photo to a 800x600 resolution. This can be done by selecting each file individually or by selecting a directory. If your LCD frame is connected to the PC, the files are automatically transferred to the internal flash memory in a subfolder. A folder is also created on the desktop with the downsized jpg photos. The original photos are untouched. If the LCD frame is not connected to your PC when the OptiPix program is running, you will get an error message; however, the files are still transformed and the subdirectory is still created on the desktop. I converted my original 1800x1200 jpg files to 800x600 resolution to save space. The converted files are about 50 to 80 KB in size.

This is actually the way I preferred to organize my photos on my CF card- putting photos in subdirectories. I ran the OptiPix program multiple times without connecting the LCD frame to the PC and each time I renamed the folder to the title of the vacation photos. Then I copied and pasted the file folders directly to the CF card. Even with the subdirectories, the LCD frame displayed all the photos within them without any problems. The order of the photos being displayed appears to be based on the time the files were created or converted.

Music:

The LCD frame also plays background music if you have music files saved in memory. Unfortunately almost all my musics are in the MP3 format and the LCD frame only works with WMA files. I had to search ways to convert my MP3s to the WMA format. I was able to use a program I already have called TotalRecorder for the job. It does a nice batch convert and saved the output file to my CF card. I encountered another problem with the WMA file. The LCD frame will not recognize WMA9 files and I had to convert the files to WMA7 format. Once I figured out the problem, I was able to encode the files at 128 kBit/s, 44.100 Hz, Stereo. The sound output is adequate. There is a volume control and mute buttons on the small remote. The small speakers are in the back of the LCD frame.

Movie:

The LCD frame will also display movie files with sound. The only movie files I tried are the ones that came out of my small Canon camera. The files I have are MVI files at 640x480. They worked fine on the LCD screen. The resolution of my file is lower than the display resolution, 800x600, therefore the movies were somewhat pixelated.

Remote Control:

The small remote control is very useful. You can select one static photo to be displayed or run the slide show. As mentioned above, it has volume control and a mute button. Adjustment of brightness/contrast and color are also available. Files can be deleted using the remote control, however, I prefer just taking the CF card out and using my PC to move files around. The remote also has an on and off button. There is really no place to store the remote, so I attached a little Velcro to the back of the LCD frame and store the remote there.


Summary:

The prices of digital picture frames are coming down quickly and the Smartparts SP8EM 8" model seems to be a good buy. I like the sizes of the wood frame and the LCD display. I saw a 10.4" LCD model today and the frame seemed a little too big for an office desk. The ability to display jpg files directly from the removable memory card is a plus. The images displayed are sharp and colors are nicely reproduced for the typical family photos. The small remote is also a nice feature.

A few thousand photos can be stored in the internal flash memory if converted using the included OptiPix program. There is no need for additional memory cards other than for convenience.

On the negative side, the LCD frame can only play WMA7 files and people may have problem converting their music to the WMA7 format. However, the LCD frame will probably be used in a silent mode most of time anyway.

Actually my wife has already decided that she is going to take the LCD frame to her office. I just have to finish processing our vacation photos from July. I am still on day 1 of our Italy trip.

Addendum: When shopping for a digital photo/picture frame it is important to note the resolution of the screen and the proportion of the screen. Most of the frames are listed by the diagonal length of the LCD screen in inches. The screen resolution for the SmartParts SP8EM is 800x600 and the proportion is close to a 4x6 print (aspect ratio 4:3). I see some 10.4" screens with similar or even lower number of pixel counts such as 640x480. There are also screens with 800x480 resolution, which displays the photo close to a 16:9 wide screen format. Most of my photos and most digital camera jpg files display better in the 4:3 aspect ratio format. After playing with the frame for a day and seeing the excellent color and resolution, I went back to Costco and purchased 2 more frames to give to the grandparents. I am going to load up the frames with family photos before I give it to them. Overall I am very happy with my purchase.

Monday, November 19, 2007

Pizza Version 1.2

Made two more pizzas last night and they actually looked like "real" pizzas and not "mutants", lol. I used lots of cornmeal so it didn't stick to the pizza peel. The amount of time needed to make the pizza is also getting shorter and this can become another quick and cheap meal option.


The photo above was my second pizza and it is already kind of dried up. The flour and cornmeal are still making it a little messy to clean up. Overall, I am still happy at the way things turned out again. It is definitely an improvement from my version 1.0 pizza and the kids are really having fun making fun of my cooking. Having some fun with the kids, that is what really matters.

Friday, November 9, 2007

What is the phone number I am calling from?

With the recent fire in Southern California, the electricity to our office went off. When it came back on, there must have been some sort of power surge that zapped our Panasonic phone system. AT&T was nice enough to allow us to set up a temporary call forwarding feature for a few days until we got a new phone system installed. Anyway, here are some interesting numbers I found while trying to debug and fix the phone lines.
  • If you want to know the phone number you are calling from and you are with AT&T, dial 959-9822
  • MCI can tell you the number you are dialing from at 800-444-4444
  • If you don't know who your long distance carrier is, call 1-700-555-4141

Thanks to AbleComm.com for the above information.

Thursday, November 8, 2007

craigslist.com

I finally sold something online via craigslist. I had 5 Kodak slide trays that have been sitting around in my office for many years collecting dust. All of the presentations these days are done on PowerPoint and the slide trays are totally useless now. The slide trays were listed on craigslist for 2 months and someone came and picked it up. Um.. I made $5.00, lol. It is good that the trays now have a new home. This is better than throwing them in the trash.

Wednesday, November 7, 2007

Pizza Version 1.1

I did my Pizza Version 1.1 for dinner tonight- two 12" pizzas. "Not bad," my wife said. I learned my lesson last week and used a lot more flour and cornmeal. With the cornmeal, the pizza didn't stick to the peel this time and it worked out much better.

The pizza dough was from Trader Joe's and I even baked some bread sticks with a garlic/spice dough. Overall, I am very happy the way things turned out today.

Oh, I still couldn't figure out how to use the fancy digital timer on the Dacor oven. Okay, plans for version 1.2 for next week:

  • adding some herbs and garlic to the pizza sauce.
  • I read somewhere you are suppose to poke the dough with a fork to get rid of bubbles. My second pizza tonight had a very large bubble. It was the size of a baseball!

Monday, November 5, 2007

Attack of the Mutant Pizza

My latest quest in life is to learn how to make a pizza from scratch. As with any tasks in life you must have the right tools and Amazon.com definitely has got my vote for the place to purchase all the required gadgets to make a pizza from scratch. Here is my list:

  • pizza stone or pizza pan is a must. I purchased a cast iron pizza pan.
  • a pizza peel to transfer the pizza
  • a pizza wheel cutter
  • a silicon mat to roll out the dough.

Well, I kind of cheated for my Pizza 1.0 version. I purchased a ready made pizza dough from WinCo Foods. After reading about 20 variations on dough recipes on the Internet, I think I may have to stick with ready made dough.

Once I have the pizza dough, pizza sauce, and some cheese, I thought to myself how hard can it be? Just put the pizza in the oven and a few minutes later, it is ready to eat. Actually, it was a lot harder than I thought. My version 1.0 pizza bombed. While trying to place the pizza on my new cast iron pizza pan, the dough stuck to the peel and didn't want to slide off. I tried desperately to keep the circular shape as I tucked and pushed on the pizza. The pizza kind of flopped upside down on the pan preheated to 425 degrees.

The end result was still edible, well, kind of, just a small portion of it. My kids ate 2 small pieces and the rest I had to trash. I was just too embarrassed for anyone else to see it. It was one ugly looking pizza. It was all twisted and looked liked a mutated tumor.

Version 1.1 of the pizza is coming this week, and I am planning some adjustment:

  • I got to get some cornmeal. I read that is the thing to use to prevent the pizza from sticking to the peel.
  • I am going to cook 2 small pizzas instead of one large one. In case I mess up the first small one, I still can try to make another.
  • I needed a little more cheese.












Monday, October 22, 2007

I Have a New Watch

My old Casio watch finally broke last week. The month stays permanently in January and changing the time is almost impossible. I had the watch for over 20 years and it has served me well. I had to change the resin watch band and battery once a while, but the watch just keeps on going.



Looking around on Amazon.com, I found another Casio that is almost exactly the same as mine- the classic Casio model F91W. You really can't beat the price. I got it from Amazon.com for $10.99. The lithium battery suppose to last 7 years, similar to my old watch. The F91W even has its own wikipedia entry. Although the watch is now famous due to its connection to terrorism. Just after I got my watch last week the price on Amazon went up 8 dollars, but it is still a bargain.







Thursday, October 4, 2007

Burden

it is my
burden
to
bear

Sunday, September 30, 2007

Marinara Sauce

Ever since we came back from Italy in July, my daughter and I have been craving for spaghetti with marinara sauce. I just can't seem to copy the same flavor or texture of the sauce in Italy. It must be the type of tomatoes they use over there. I looked all over town and couldn't find any imported cans of tomatoes for sale; Trader Joe's does not have it either.

At the end of the meal in Italy, after finishing all the spaghetti, there is always lots of olive oil and sauce left over at the bottom of the plate. I have tried really hard to reproduce the same. Well, here is my version 1.1 today (version 1.0 was 2 weeks ago and it didn't turn out too good):

2 cans of Hunts peeled tomato each 14.5 oz.
4-5 cloves of garlic
1/4 to 1/3 cup of olive oil
1/2 tsp dried basil
1/2 tsp dried oregano
salt, pepper
1 tsp sugar
  1. Chop up the garlic into little pieces. My kids like the taste of garlic but do not want to bite into a big piece.
  2. Slightly brown the garlic in the olive oil over medium heat. In my version 1.0 of the sauce, I over cooked the garlic and it was slightly burnt and it had a funny smell, so don't over cook here.
  3. Add the canned tomatoes
  4. Add the basil. My fresh basil leaves left over from version 1.0 were kind of welted and I had to use the dried up ones today. (I used a "rounded" 1/2 tsp) The dried up ones turned out ok and it is easier to keep around.
  5. Add the oregano. (I used a "rounded" 1/2 tsp)
  6. Add some salt (I did two pinches today and it turned out ok) and some pepper.
  7. Add the sugar (the tomatoes in Italy tasted sweet, my wife suggested it)
  8. I added a little water (1/3 cup) today so the final sauce would not be too sticky.
  9. Bring it to a boil and then simmer for 40-60 minutes over low heat. Stir and mash up the tomatoes as it simmers.
  10. 1 lb. of spaghetti should be ok for my family of 4. I cooked too much today.
  11. One trick I did today was to scoop up the olive oil on top of the sauce pan and add it to each plate first and coat the freshly cooked spaghetti, and then add the sauce later. This way each person would get similar amount of olive oil.

Feedback:

  1. The taste was good, almost there.
  2. Too little sauce (use 3 cans next time?)
  3. Not enough olive oil left over at the bottom of the plate (use 1/2 cup of olive oil next time?)
  4. They like the angel hair better than the thin or regular spaghetti
  5. not much protein with this meal though
  6. need to remember to get some bread

Overall I am happy with the version 1.1. It is getting close to the real thing. Oh, I need to buy the olive oil/ vinegar dispenser thingy. The one that has both oil and vinegar in one glass holder one inside the other.

Sandwich

parents are getting old
sad to see them change so quickly
not much i can do

sad
don't like being in the sandwich

cried by myself today

Saturday, September 8, 2007

Heimlich

Did my first real life Heimlich yesterday.

Man, I thought she was going to die and it happened so quick. At first I thought she was just waving at me, then I saw her face turning a dark shade of purple.

I am still kind of in shock.

Wednesday, September 5, 2007

Stir-Fry Nian Gao

Hey don't laugh, I'm not good at writing down recipes.

version 1.0 - 9/4/2007, my first try was not bad. It was a little salty and the Nian Gao could have been cooked a little longer and softer.

version 1.1- 9/5/07, modified by adding some more water to the final step, and took out extra added salt or soy sauce at the end

version 1.2- 9/10/07, pre-soaking the Nian Gao made them softer, increased the chicken to 3 pieces, and re-added the soy sauce at the end, just a little.

version 1.21- 9/18/07, added Chinese cabbage after taking the chickens out. Tried using 1 1/2 bag of the Nian Gao

Procedure:

  • buy the Nian Gao that comes frozen or refrigerated and in a vacuum bag
  • 1 bag can serve about 3 people. Use 1 1/2 bag to serve 4 with some left overs
  • thaw the Nian Gao in cold water, make sure you kind of wash them a little because I found some hard brown stuff stuck to some. The thawing takes around 15 min
  • pre-soak them in cold water for 1 to 2 hours
  • defrost 3-4 pieces of frozen chicken thigh, microwave on auto defrost setting 3, turn, then auto defrost setting 3 again
  • the chicken is still half frozen and easier to cut
  • cut up 1 or 2 "stick(s)" of scallion or green onion into small pieces... *ok, there must be an official word for a "stick" of green onion*
  • cut the chicken into small strips and marinate in soy sauce
  • put some oil in the pan and stir-fry the green onion for a while, then add the chicken, cook until done
  • take the chicken out and set aside but leave the juices
  • add some Chinese cabbage now- cut them into thin slices
  • add the Nian Gao into the pan and stir-fry a while
  • add one can of chicken broth
  • add another cup of water
  • add a little more soy sauce if needed
  • cook until the Nian Gao is soft and most of the liquid is gone
  • add the chicken back into the pan and cook together for a short time

This is not an official Shanghai Stir-Fry Nian Gao recipe. It is just my version that can be cooked and ready to eat in 90 min. I like my Nian Gao soft since I don't like to chew.

I'm trying this again next week. Wish me luck.

My Ubuntu Box is Working!!

Well, thanks to HP, I now have Ubuntu working nicely with Skype. I was recently tortured mentally by the incompetent HP Tech Support in India for hours on the phone. My bad experience with HP gave me enough motivation to get the Linux box working with Skype.

My blog about my HP encounters are here, and here. I am so glad that the nightmare with HP is over. I promised myself that I will never buy another HP computer system again.

The problem with using the mic for Sound Recorder on Ubuntu is still not solved, however, the mic is working with Skype and that is what I needed anyway. The trick is to select the actual sound card device under options in Skype and not allow Skype to use the "default device." I'll try to upload some screen capture in Linux in another blog.

Monday, August 27, 2007

I am sticking with Windows

Well, my Ubuntu box is running well. I am able to surf the web, write stuff on the word processor, etc. Almost everything most people use and do on the computer are already included with Ubuntu.

I do have one problem, that seems to affect many other users as well. My problem is getting the microphone to work, especially with Skype. I spent many hours today trying all different settings and reading hundreds of forum threads, used 5 different microphones, and concluded it is just not going to work.

My sound card is the Sound Blaster Live! Value from Gateway. This worked well under Windows. For now at least I am able to hear sound coming to the speaker, I just cannot record sound or use Skype.

I am not sure why people are so crazy about Ubuntu. Yes, it is free, but the way Linux works still involves a lot of command line debugging and compatibility is still a problem. I will probably leave Ubuntu on the system and play with it when I have some more time. For now, I am still sticking with Windows.

Disk Partition Setup in Ubuntu

I was messing around with an old Gateway PC this weekend cleaning out the kids' old computers and getting ready for school to start tomorrow. Instead of throwing away the PC's, I decided to install Ubuntu Linux on one of the systems. The latest version of Ubuntu is Feisty Fawn 7.04. The install is easy enough, download the CD image file and it pretty much runs by itself. The problem was trying to figure out what is the best way to partition the hard disk.

The old PC had Windows ME, which is probably the worst version of Windows around, so I decided to use the entire disk for Ubuntu and not install a dual boot partition. There are basically 3 ways to partition Ubuntu:

1. Use the entire disk for Linux in one big partition for all the programs and system files. A SWAP partition will also be added automatically. Total of 2 partitions will be created. This is one of the automatic options.
2. Use multiple partitions for speed and security in the future. The partitions can be /, /home, /temp, /var, etc.
3. The third way and probably middle of the road method is to create three partitions: /, /home, and SWAP. The root partition is the "/", which is used for all the system files. The /home partition is used for all user data, similar to My Document under Windows XP. This is the best way for future upgrades.

The following are a series of screen shots for doing the partitioning task manually. Sorry for the fuzzy pictures. I have no idea how to capture the screen during an install.


The above screen shows that I originally partitioned my hard drive using the automatic method and the installer made 2 partitions only. One is the ext3 partition for all the files and the other a SWAP partition. Here I am selecting to make a "New partition table."


Now all the old partitions are deleted and it showed the entire disk as free space.


By double clicking on the free space line, a new window opens to create a new partition. This is going to be my root or "/" partition. I am giving it a fairly large size of 10 GB. Note that I am using the ext3 format. Why 10 GB? Someone on the net recommended it. It will give me some room for future versions of Ubuntu.


After the ext3, 10 GB, partition is defined, I double click on it again to select "Mount Point." This is where I selected "/" for the root partition.

Now repeat the procedure for the next partition. Remember to leave some room for the SWAP partition. The recommended size for SWAP is at least the size of your ram to a max of 2 GB. I just planned to use 2 GB, and made my /home partition accordingly. Don't forget to select /home for the second partition. Use "SWAP" as the type for the third partition, which is around 2 GB in my example. Also note that once "SWAP" is selected, there is no option for "Mount Point."

Once the 3 partitions are created, rest of the install process is pretty simple.

I hope this will save someone a few minutes installing Ubuntu.

Saturday, August 25, 2007

My Flickr Photos in a Mashup Photo Stack



The mashup projects are taking a little more time to load than I expected. I am unsure if this is due to the fact that I am getting photos to download or if the slow down is the norm for Microsoft Silverlight.

Whack A Mole with Regina Spektor




Click on the Green Screen to start. The hammer is a little small. Again, you will need Microsoft Sliverlight to see the project.

Regins Spektor Photo Carousel

This is a quick mashup project. You will need to install Microsoft Silverlight to see. Addendum: Mac users and Firefox users will not be able to see this. Apparently the carousel codes are not compatible with the Mac and FF.

Tuesday, June 19, 2007

Mitch Kapor: Virtual Worlds Are Like A Drug Experience -- InformationWeek

Mitch Kapor is the chairman of Linden Lab. He was quoted saying users of Second Life are bunch of crazy people. I think he is correct in his assessment. I am looking forward to become one of these crazy people.

Kapor, who is chairman of Linden Lab, which operates Second Life, said he realized the potential of Second Life at an in-world Suzanne Vega concert last year. Vega

"What's driving virtual worlds is a shared sense, by a few hundred thousand crazy people, that this is important, and they're going to drop everything and go after this," he said.

Mitch Kapor: Virtual Worlds Are Like A Drug Experience -- Virtual Worlds -- InformationWeek

Wednesday, June 13, 2007

FDA panel rejects Sanofi-Aventis' Acomplia drug - MarketWatch

Another potentially promising drug, rimonabant, bites the dust.

FDA panel rejects Sanofi-Aventis' Acomplia drug - MarketWatch

In a report prepared by the panel and published Wednesday, concerns were raised about the safety of Acomplia, particularly its effect on users' mental health. Sanofi-Aventis submitted data and analyses on Acomplia for the panel's review late last year.

"Adverse events" encountered during the testing of the drug included "depressive events, anxiety, psychomotor agitation, and sleep disorders," according to the panel's report.

The FDA's Division of Metabolism and Endocrine Products has received a number of "event" reports from Sanofi-Aventis related to Acomplia, the report said, including "4 reports of delusional symptoms, 6 reports of psychotic behavior (including a man who attempted to strangle his daughter), and 5 reports of aggression (including a man who beat his wife.)"

Rimonabant, the generic form of Acomplia, is approved in 37 countries and marketed in 18, according to Sanofi-Aventis.

Saturday, June 9, 2007

Blog This for Firefox

Check out this add-on for Firefox and Microsoft Live Writer:

Windows Live Gallery

Description:

The Blog This for Firefox adds a button to Firefox which starts a new Windows Live Writer blog post prepopulated with content and title from the current web page. Blog the whole page, or just selected snippets. Interacts with other registered plugins to parse and structure web content where appropriate. Blog quickly when you find something of interest on the web.

I am trying to write this blog using some of the features of the add-on. Once the page is open, the Windows Live Gallery link was automatically added.

Instant Karma- June 12, 2007



I am just interested in one song...

Real Love

Oh but California

California I'm coming home
I'm going to see the folks I dig
I'll even kiss a Sunset pig
California I'm coming home.

Thursday, June 7, 2007

Google Machine and Web 2.0

Lately I have been sucked up by the google machine. Ever since I got my gmail account I have been adding additional google services- blogger, google map, google reader, adSense, picasa, and a few google group subscriptions.

Yesterday, I even got enough courage together and downloaded Firefox. OK, it is not a google service but it goes along with my new trend in non-microsoft downloads.

My new Web 2.0 experiment is actually going pretty well. My desktop is filled with new icons that are changing my online experience.

Installation of Linux is probably going to be next for me or I may try to immerse my alter ego in second life. I am a little late to the party but the web is becoming interesting again for me.

Think Before You Post



Monday, June 4, 2007

Problem staying logged in on Blogspot

If you are having problem staying logged into Blogger under Windows XP and Internet Explorer and have to enter your email and password repeatedly, then go into Tools-> Internet Options-> Privacy-> Sites, and then add www.google.com to the managed websites list. It worked for me.

Saturday, June 2, 2007

Stents- June 2007

There are two drug-eluting stents available in the U.S. at this time- Johnson & Johnson/Cordis CYPHER and the Boston Scientific TAXUS.

Medtronic ENDEAVOR stent is currently under review by the U.S. FDA and approval is anticipated in the second half of 2007.

Abbott XIENCE V stent application to the U.S. FDA was submitted June 1, 2007. Approval is expected in the first quarter of 2008.

The Medtronic ENDEAVOR stent is based on the cobalt alloy DRIVER stent. It has a Phosphorylcholine polymer licensed from Abbott Laboratories. The ENDEAVOR stent releases a drug called ABT-578, which is also licensed from Abbott Laboratories.

The Abbott XIENCE V stent is based on the Multi-Link Vision stent with Everolimus as the eluting drug. The XIENCE V stent will also be co-marketed by Boston Science as the PROMUS Everloimus Eluting stent. The Multi-Link Vision stent is the same stent developed and marketed by Guidant in the past. The "V" in XIENCE V probably is in reference to "Vision" and not "version 5" of the stent.

Prior to 2006, Abbott did not have a stent product. How Abbott purchased the XIENCE stent from Guidant is quite interesting. In January 2006, Boston Scientific was locked in a bidding war with Johnson & Johnson for Guidant. Boston Scientific really wanted to buy the rhythm management (pacemaker, ICD) division of Guidant. Abbott was able to purchase the vascular device (stent and balloon) division of Guidant from Boston Scientific as part of the deal. The deal between Abbott and Boston Scientific was a mixture of direct payment, stock sales, and low interest loan. Boston Scientific was finally able to purchase Guidant in 2006.

Thursday, May 31, 2007

Effect of Coenzyme Q10 on Myopathic Symptoms in Patients Treated With Statins

Am J Cardiol 2007;99:1409-1412

This was a small pilot study to see if  supplementation with  coenzyme Q10 would improve muscle symptoms in patients taking a statin medication.  Statin medications are commonly used to lower cholesterol levels.  Many patients experience severe muscle aches and pains while on statin medications.  The use of coenzyme Q10 is based on fact that cholesterol and coenzyme Q10 are both lowered by statin medications and a deficiency of coenzyme Q10 may be causing some of the muscle symptoms.

Only 32 patients were involved in this small pilot study. Eighteen patients were given 100 mg of coenzyme Q10 daily and fourteen patients were given 400 IU of vitamin E daily. Vitamin E was used as a control. The study was a controlled, double-blind, randomized trial. The patients were treated for 30 days.

The results of the study showed that coenzyme Q10 supplement decreased muscle pain by 40% and improved the interference of pain with daily life activities by 38%. In the group treated with vitamin E, no affect with pain symptoms or interference of pain with daily activities were noted.

Wednesday, May 30, 2007

Convert YouTube video to watch on an iPod

Here is a free site that will allow you to convert a YouTube video (Flash video) to MPEG4 format to watch on you iPod: vixy.net

It can also convert the YouTube video to a 3GP file format compatible with most cell phones.