Am J Cardiol 2007;99:1409-1412
This was a small pilot study to see if supplementation with coenzyme Q10 would improve muscle symptoms in patients taking a statin medication. Statin medications are commonly used to lower cholesterol levels. Many patients experience severe muscle aches and pains while on statin medications. The use of coenzyme Q10 is based on fact that cholesterol and coenzyme Q10 are both lowered by statin medications and a deficiency of coenzyme Q10 may be causing some of the muscle symptoms.
Only 32 patients were involved in this small pilot study. Eighteen patients were given 100 mg of coenzyme Q10 daily and fourteen patients were given 400 IU of vitamin E daily. Vitamin E was used as a control. The study was a controlled, double-blind, randomized trial. The patients were treated for 30 days.
The results of the study showed that coenzyme Q10 supplement decreased muscle pain by 40% and improved the interference of pain with daily life activities by 38%. In the group treated with vitamin E, no affect with pain symptoms or interference of pain with daily activities were noted.
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